How much does Orkambi cost?

How much does Orkambi cost?

Orkambi has a list price of around $272,000 per year, while Symdeko lists at around $292,000. Analysts expect the early approval to accelerate the launch date for Trikafta, which they expect will make $630 million in 2020.

How much does medicine cost for cystic fibrosis?

FDA approves drug to treat cystic fibrosis in patients 12 and older—and it will cost $311,503.

What is Kaftrio?

Kaftrio is a medicine used to treat patients aged 12 years and above who have cystic fibrosis, an inherited disease that has severe effects on the lungs, the digestive system and other organs.

Is Orkambi available on the NHS?

NHS England has today announced it has secured a definitive agreement with Vertex Pharmaceuticals to make available all three of their UK-licensed cystic fibrosis medicines. This means NHS patients will now have full access to Orkambi, Symkevi and Kalydeco, and around 5000 people may now take up these treatments.

How much does Trikafta cost annually?

ICER’s recommended health-benefit price benchmark (HBPB) for Trikafta is $67,900-$85,500 per year, which would require at least a 73% discount off the treatment’s current list price.

Is cystic fibrosis expensive?

Living with cystic fibrosis is expensive. On average, people with CF rely on three oral and three inhaled medications daily and see a multidisciplinary care team four times a year. This treatment and care regimen can be expensive even for individuals with comprehensive insurance.

How much does Kaftrio cost the NHS?

Kaftrio 75mg/50mg/100mg tablets (Vertex Pharmaceuticals (Europe) Ltd) ▼

Active ingredients Size NHS indicative price
Ivacaftor 75 mg Tezacaftor 50 mg Elexacaftor 100 mg 56 £8346.30 (Hospital only)

How much does Orkambi cost with PBS?

With Orkambi’s starting price being $250,000, ICER is suggesting it is worth no more than $75,000.

What is Paravit CF?

Paravit™-CF is a fat-soluble vitamin supplement specifically designed for people with Cystic Fibrosis and is available in Liquid and Softgel Capsule form. Paravit™-CF is regulated and classified as a Food for Special Medical Purposes (FSMP).

How much does Orkambi cost UK?

Vertex’s UK list price for Orkambi is £104,000 ($136,000) for a year’s treatment. If England were to pay this price for the approximately 2,834 people who are eligible, it would cost around £295m, which would make it one of the country’s biggest drug expenditures.

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