What is the serogroup of Neisseria meningitidis?
N. meningitidis can be classified into 12 serogroups based on its capsular polysaccharide; serogroups A, B, C, W, X, and Y are the primary causes of meningococcal disease worldwide.
What is Neisseria meningitidis serogroup B?
Neisseria meningitidis is an obligate human pathogen and is the most prevalent serogroup causing meningococcal disease in the Western countries. In the majority of cases it only colonizes the host for a period of time but it can also invade and cause systemic diseases like sepsis and meningitis.
Does Neisseria meningitidis serogroup A have a capsule?
Pathogenic Neisseria meningitidis isolates contain a polysaccharide capsule that is the main virulence determinant for this bacterium.
What is meningococcal Acwy?
What is the MenACWY vaccine? The MenACWY vaccine is given by a single injection into the upper arm and protects against 4 strains of the meningococcal bacteria – A, C, W and Y – which cause meningitis and blood poisoning (septicaemia).
Is meningococcal encapsulated?
Neisseria meningitidis meningitidis organisms are encapsulated, or surrounded by a polysaccharide capsule. This capsular polysaccharide is used to classify N. meningitidis into 12 serogroups.
Do you need meningococcal B?
It is recommended for all kids and teens age 11 and older. Some types of MenACWY are given to younger children (as early as 8 weeks of age) if they have a higher risk of getting meningococcal disease. The meningococcal B vaccine (MenB) protects against a fifth type of meningococcal bacterium (called type B).
Is menactra the same as meningococcal B?
There are 2 types of meningococcal vaccines available in the United States: Meningococcal conjugate or MenACWY vaccines (Menactra®, Menveo®, and MenQuadfi®) Serogroup B meningococcal or MenB vaccines (Bexsero®and Trumenba®)
What is polysaccharide capsule?
Polysaccharide capsules are structures found on the cell surface of a broad range of bacterial species. The polysaccharide capsule often constitutes the outermost layer of the cell, and therefore is often involved in mediating direct interactions between the bacteria and its environment.
Does Streptococcus pneumoniae have a capsule?
The polysaccharide capsule surrounding S. pneumoniae has been well established as a major virulence factor in nonocular pneumococcal infections such as systemic infections, lung infections, and bacteremia. The function of the capsule in these infections is to allow the bacterium to evade phagocytosis.
What is the difference between meningococcal Acwy and meningococcal B?
These vaccine products are not interchangeable; the same vaccine product is required for all doses. MenACWY vaccines provide no protection against serogroup B disease, and meningococcal serogroup B vaccines (MenB) provide no protection against serogroup A, C, W, or Y disease.
Is meningococcal Acwy the same as MCV4?
A3: One dose of meningococcal conjugate vaccine (MenACWY; sometimes abbreviated as MCV4; brand names Menactra or Menveo) is required for entry into grades 7 through 11. Q4: How many doses of meningococcal vaccine are required for grade 12?
Is meningococcal disease acute chronic or latent?
Meningococcal disease is an acute, severe illness caused by the bacterium Neisseria meningitidis. A leading cause of bacterial meningitis and sepsis in the United States, N.