What is the difference between Visipaque and omnipaque?

What is the difference between Visipaque and omnipaque?

Even at its highest concentration, 320 mg I/ml, Visipaque – based on the nonionic dimer iodixanol – is isoosmotic to blood plasma, whereas Omnipaque (300 mg I/ml) – based on the nonionic monomer iohexol – has an osmolality of about twice that of the plasma.

What is Visipaque contrast?

What Is Visipaque? Visipaque (iodixanol) Injection is a radiographic contrast medium indicated for intra-arterial digital subtraction angiography, angiocardiography (left ventriculography and selective coronary arteriography), peripheral arteriography, visceral arteriography, and cerebral arteriography.

How long do the side effects of contrast dye last?

Patients at increased risk of late skin reactions are those with a history of previous contrast medium reaction and those on interleukin-2 treatment. Most skin reactions are self-limiting and resolve within a week.

What happens when you take metformin after contrast?

Contrast dye can increase the chances of metformin causing lactic acidosis in patients with decreased kidney function.

Is visipaque safer than omnipaque?

Visipaque scored a big win in 2003 with a study in The New England Journal of Medicine finding that the iso-osmolar agent was significantly safer than a low-osmolar agent (Omnipaque) in preventing contrast-induced nephropathy in coronary angiography patients.

Is visipaque a high or low-osmolar contrast?

Key Words: Visipaque 9 Iodixanol has the lowest osmolality of all available contrast media (290 mOsm/kg H2O), which represents a nearly two-thirds reduction in osmolality compared with low- osmolar contrast agents such as iohexol (844 mOsm/kg H2O).

Is Visipaque safer than omnipaque?

When is Visipaque used?

Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination. Visipaque is used to help diagnose certain disorders of the brain, blood vessels, heart, kidneys, and other internal organs.

How does contrast dye affect the kidneys?

The dye may injure the kidneys by causing the blood vessels of the kidney to narrow, and damaging the structures inside the kidney, said study author Dr. Javier Neyra.

Can contrast dye cause high blood sugar?

In most cases contrast dyes used in tests, such as CT (computerized tomography) and angiograms, have no reported problems. About 2 percent of people receiving dyes can develop CIN. However, the risk for CIN can increase for people with diabetes, a history of heart and blood diseases, and chronic kidney disease (CKD).

Can you give metformin with contrast dye?

Metformin medications should be stopped at the time of or prior to CT studies with IV Contrast, AND withheld for 48 hours after the procedure.

What is the chemical structure of Visipaque?

Visipaque (C 35 H 44 I 6 N 6 O 15) has the following chemical structure: Visipaque Injection is provided as a ready-to-use sterile, pyrogen-free, colorless to pale yellow solution, in Pharmacy Bulk Package, in concentrations of 270 and 320 mg of organically bound iodine per mL (550 and 652 mg of iodixanol per mL,…

What is the sodium/calcium ratio of Visipaque 270?

Visipaque 270 (270 mgI/mL) contains 0.074 mg calcium chloride dihydrate per mL and 1.87 mg sodium chloride per mL, and Visipaque 320 (320 mgI/mL) contains 0.044 mg calcium chloride dihydrate per mL and 1.11 mg sodium chloride per mL, providing for both concentrations a sodium/calcium ratio equivalent to blood.

What are the side effects of Visipaque?

Cardiovascular Adverse Reactions: Life-threatening or fatal cardiovascular reactions including hypotension, shock, cardiac arrest have occurred with the use of Visipaque. Most deaths occur during injection or five to ten minutes later, with cardiovascular disease as the main aggravating factor.

What is Visipaque 320 mg iodine?

Visipaque 320 mg Iodine/mL is an iso-osmolar agent that is now approved for use in coronary computed tomography angiography (CCTA) to assist in the diagnostic evaluation of adult and pediatric patients 12 years of age or older with suspected coronary artery disease in the United States.

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