What is klucel used for?

What is klucel used for?

Klucel™ HPC polymers have been used previously to control drug release from hot-melt-extruded films (23) and as a granulation binder (24). HPC polymers are non-ionic polymers that release the drug by a mechanism of swelling and erosion.

What is klucel H?

Klucel™ EF Hydroxypropylcellulose is a nonionic polymer that is completely soluble in both water and polar organic solvents like ethanol. This grade has a viscosity of 200-600. Klucel™ H CS has excellent film-forming properties, thickens non-aqueous systems and 100% ethanol solutions, and provides lubricious skin feel.

What is Klucel EXF?

Klucel™ EXF Ultra HPC is an ultra-fine tablet binder that assures formulation predictability, reliability and robustness. Klucel™ EXF Ultra HPC provides enhanced tablet strength and low friability with the most difficult to compress active pharmaceutical ingredients even at low usage levels.

How do you dissolve klucel?

Slowly sprinkle the Klucel G powder in to the alcohol and stir or shake to mix. The mixture will appear clumpy and thick at first but allow at least 24 hours for the material to completely dissolve. Mix and store in a sealed container to prevent evaporation. Mix or shake again prior to application.

What are the side effects of hydroxypropyl cellulose?

Side Effects

• Blurred vision.
• eye redness or discomfort or other irritation not present before use of this medicine.
• increased sensitivity of eyes to light.
• matting or stickiness of eyelashes.
• swelling of eyelids.
• watering of eyes.

How do you dissolve HPC?

(1) Solubility in Water HPC dissolves in water. (2) Solubility in Polar Organic Solvent It can dissolve in polar organic solvents such as methyl alcohol,alcohol,chloroform,acetone etc. (3)Hot Gelling Feature The water solution goes up or down with temperature,and takes on a reversible gelling process.

Is hydroxypropyl cellulose hydrophilic?

HPC is an ether of cellulose in which some of the hydroxyl groups in the repeating glucose units have been hydroxypropylated forming -OCH2CH(OH)CH3 groups using propylene oxide. HPC has a combination of hydrophobic and hydrophilic groups, so it has a lower critical solution temperature (LCST) at 45 °C.

Is hydroxypropyl cellulose natural?

Hydroxypropyl methyl cellulose (HPMC; CAS No. 9004-65-3) is an odorless and tasteless, white to slightly off-white, fibrous or granular, free-flowing powder that is a synthetic modification of the natural polymer, cellulose. It is used in the food industry as a multipurpose food ingredient.

Is hydroxypropyl cellulose harmful?

Hydroxypropyl methylcellulose cannot be digested by humans and passes through the digestive system. It is now an EU and FDA-approved food additive and is considered non-toxic to humans.

What does hydroxypropyl cellulose do?

Hydroxypropyl cellulose belongs to the group of medicines known as artificial tears. It is inserted in the eye to relieve dryness and irritation caused by reduced tear flow that occurs in certain eye diseases.

What is hydroxypropyl cellulose used for?

It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis, and as a lubricant for artificial eyes.

What is hydroxypropyl cellulose type H?

Hydroxypropyl cellulose is a cellulose ether used to treat dry eyes. It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis, and as a lubricant for artificial eyes.

What is Klucel HPC film?

It combines organic solvent solubility, thermoplasticity, and surface activity with the aqueous thickening and stabilizing properties characteristic of other water-soluble cellulose polymers available from Ashland. Klucel HPC films are flexible without plasticizers and non- tacky at high humidity.

What is the viscosity of Klucel H CS?

Klucel™ H CS has excellent film-forming properties, thickens non-aqueous systems and 100% ethanol solutions, and provides lubricious skin feel. This grade has a viscosity range of 1,500-3,000 cps. Klucel™ CS Grade is a nonionic, water-soluble cellulose ether with a versatile combination of properties.

What is Klucel hydroxypropylcellulose?

Klucel™ Hydroxypropylcellulose, Ashland – ChemPoint Klucel™ Hydroxypropylcellulose is a nonionic, water-soluble cellulose ether with a versatile combination of properties in personal care applications. ChemPoint ChemPoint main navigation

What is Klucel CS grade?

Klucel™ CS Grade is a nonionic, water-soluble cellulose ether with a versatile combination of properties. It combines solubility in aqueous and polar organic solvents, thermoplasticity, and surface activity with the thickening and stabilizing properties of other water-soluble cellulose polymers.