What is FFR of LAD?

Fractional flow reserve (FFR) can accurately identify those patients with equivocal lesions in the proximal left anterior descending (LAD) artery who may not need revascularization and will see comparable outcomes with medical management, according to a study published online October 26, 2011, ahead of print in JACC: …

What does FFR mean in cardiology?

Background. Fractional flow reserve (FFR) measurement involves determining the ratio between the maximum achievable blood flow in a diseased coronary artery and the theoretical maximum flow in a normal coronary artery. An FFR of 1.0 is widely accepted as normal.

What is mid LAD in heart?

The mid LAD is the most commonly involved coronary artery. The myocardial bridge usually involves the proximal segment, however other segments can be affected. The length of the myocardial bridging is variable, but it typically ranges from 10 mm to 50 mm.

Why is FFR important?

FFR is a valuable tool to determine the functional significance of coronary stenosis. It combines physiological and anatomical information, and can be followed immediately by percutaneous coronary intervention (PCI) if necessary.

How often is FFR used?

Despite long-term data showing improved outcomes with FFR-guided decision-making, its use remains significantly underutilized in practice, with FFR being used in 6.1% of interventions for intermediate coronary lesions (40-70% stenosis).

When is an FFR done?

FFR uses a small sensor on the tip of the wire (commonly a transducer) to measure pressure, temperature and flow to determine the exact severity of the lesion. This is done during maximal blood flow (hyperemia), which can be induced by injecting products such as adenosine or papaverine.

Is FFR safe?

This registry demonstrated that the FFR value was linearly associated with the risk of cardiac events in deferred lesions. However, deferring revascularization in favor of medical therapy in lesions with FFR ≥0.76 was a reasonable and safe treatment strategy.

What is an abnormal FFR?

There is no absolute cut-off point at which FFR becomes abnormal; rather, there is a smooth transition, with a large grey zone of insecurity. In clinical trials however, a cut-off point of 0.75 to 0.80 has been used; higher values indicate a non-significant stenosis, whereas lower values indicate a significant lesion.

Is mid LAD blockage serious?

A narrowing or blockage in the LAD is more serious than narrowing or blockage in the other arteries. Bypass surgery usually is the best choice for a blocked LAD.

Can you live with 100 blocked LAD artery?

Widowmaker recovery It occurs when 100 percent of the left anterior descending (LAD) artery is blocked. This particular type of heart attack can be fatal because of the LAD artery’s significant role in providing blood to your heart.

How FFR test is done?

What is the cost of FFR test?

Table 1

Costs per procedure	Procedure fee	Device cost
cCTA	$400	–
FFR	$42	$1,800
Price FFRct	–	$2,000

Does Lad affect FFR?

Disease in the LAD will certainly affect FFR assessment of. the LMCA when the pressure-sensor wire is in the LAD.13,14. For this reason, it is recommended to position the pressure. sensor in an artery that is free of significant stenosis.

How do you measure FFR in Lad disease?

In practice, the LM FFR in the setting of LM and LAD disease is assessed by placing the pressure wire sensor distal to the LAD lesion, administering adenosine hyperemia (either intravenously or intracoronary), and calculating the FFR across both lesions, which is called FFR epicardial.

What is the FFR of the left main artery across Lad?

Across Mid LAD Across LM After rotational atherectomy and 2.5×28 mm DES, post-dilated to 3.0 mm FFR of Left Main FFR of Left Main = 0.72 (In absence of LAD lesion) Proximal to LAD stent Across LM Effect of Tandem Lesions 0.84 0.64 Myocardium 0.72 Myocardium