What is contraindicated with succinylcholine?

What is contraindicated with succinylcholine?

Contraindications: hyperkalemia, bedridden patients, rhabdomyolysis, muscle trauma, burns, infusion of neuromuscular blocking agents, acute renal failure, chronic renal failure, intraocular hypertension, intracranial hypertension, statin use, malignant hyperthermia, neuromuscular disease, spinal cord sectioning.

In which below patient succinylcholine is contraindicated?

Succinylcholine is contraindicated in patients after the acute phase of injury after major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury. Succinylcholine administration to such patients can cause severe hyperkalemia, which can result in cardiac arrest.

When should succinylcholine be avoided?

The administration of succinylcholine chloride is contraindicated in patients with known decreased plasma cholinesterase activity, recent burns or trauma within 24 to 72 hours, and muscle myopathies.

Is succinylcholine contraindicated in rhabdomyolysis?

Anesthesia for a patient with a known or suspected myopathy has a potential risk of rhabdomyolysis, and succinylcholine is contraindicated.

What is a possible complication associated with succinylcholine administration?

Common side effects of succinylcholine include: Jaw rigidity. Low blood pressure (hypotension) Muscle fasciculation may result in postoperative pain. Muscle relaxation resulting in respiratory depression to the point of breathing cessation (apnea)

What must be administered prior to succinylcholine?

Succinylcholine may cause a transient increase in intracranial pressure; however, adequate anesthetic induction prior to administration of succinylcholine will minimize this effect. Succinylcholine may increase intragastric pressure, which could result in regurgitation and possible aspiration of stomach contents.

Who can administer succinylcholine?

The registered nurse (RN) may administer Propofol, Etomidate and neuromuscular blocking agents (only Succinylcholine, Rocuronium and Vecuronium) to the non-intubated patient in a hospital setting for the purpose of rapid sequence intubation when the clinical presentation of impending respiratory failure is imminent.

Why is succinylcholine contraindicated in burn patients?

Succinylcholine is safe in the first 24 h after a burn—after this time, its use is contraindicated due to the risk of hyperkalaemia leading to cardiac arrest, thought to be due to release of potassium from extrajunctional acetylcholine receptors. This can persist up to 1 year post-burn.

Why is succinylcholine contraindicated in stroke?

Patients with neuromuscular disease such as a stroke have risk of serious hyperkalemia after succinylcholine. This usually peaks 7-10 days after insult, but increased K+ release may occur as soon as 2-4 days after denervation injury, or after several days of immobility.

Why is rocuronium preferred over succinylcholine?

Apnea time: Rocuronium has a 40-second longer safe apnea time when compared to succinylcholine. Safe apnea time is defined as the time required for a patient to clinically desaturate, with an SpO2 < 88% after paralysis.

What are the contraindications of rocuronium?

Who should not take ROCURONIUM BROMIDE?

  • low amount of magnesium in the blood.
  • low amount of calcium in the blood.
  • acidosis, a high level of acid in the blood.
  • respiratory acidosis, an acid-base disorder.
  • alkalosis.
  • respiratory alkalosis, an acid-base imbalance of the blood.
  • low amount of potassium in the blood.

What are the contraindications for succinylcholine?

Succinylcholine is contraindicated in patients with a personal or familial history of malignant hyperthermia and/or skeletal muscle myopathy. Malignant hyperthermia may be precipitated by succinylcholine; concomitant use of volatile anesthetics may further increase this risk.

Is physostigmine contraindicated with succinylcholine?

Physostigmine: (Contraindicated) Physostigmine is contraindicated in patients receiving succinylcholine due to reduced plasma cholinesterase activity and prolonged neuromuscular blockade. Pindolol: (Moderate) Concomitant use of neuromuscular blockers and beta-blockers may prolong neuromuscular blockade.

When should succinylcholine be avoided in patients with burn injuries?

 Succinylcholine should be avoided in patients with a significant burn or traumatic injuries that are 24 to 72 hours post-injury due to the high probability of acute hyperkalemia that may become exacerbated as a result. Marked and/or untreated hyperkalemia may result in dysrhythmias or even death.

Why is succinylcholine ineffective on the smooth and cardiac muscles?

Thus succinylcholine is ineffective on the smooth and cardiac muscles of the body.  Plasma pseudocholinesterase is responsible for the rapid hydrolyzation and metabolism of the drug in the bloodstream. A very minimal percentage of succinylcholine encompasses the neuromuscular motor endplates post-administration.

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