What does metabolic activity on a PET scan mean?

What does metabolic activity on a PET scan mean?

Metabolic activity, as defined by the uptake of 18F-fluorodeoxyglucose (FDG) on positron emission tomography (PET), takes advantage of the physiologic preferential use of anaerobic glycolysis over oxidative phosphorylation used by malignant cells for their energetic needs.

What does no metabolic activity mean on a PET scan?

Areas of low or no metabolic activity can indicate areas of reduced blood flow or blockages due to stroke or heart attacks. Use of FDG in full body scans can help determine if a cancer has metastasized to other areas of the body.

What does metabolically active mean?

1 the sum total of the chemical processes that occur in living organisms, resulting in growth, production of energy, elimination of waste material, etc.

What does diffuse uptake mean?

Diffuse uptake was defined as FDG uptake in the whole thyroid gland, whereas diffuse-plus-focal uptake was defined as a thyroid lesion with both diffuse uptake and focal FDG uptake. The maximum standardized uptake value of the thyroid lesions was recorded and reviewed.

What cancers can be detected by PET scan?

PET scans can help detect cancer and how far it has spread. PET scans can show solid tumors in the brain, prostate, thyroid, lungs, and cervix. The scans can also evaluate the occurrence of colorectal, lymphoma, melanoma, and pancreatic tumors.

Can benign tumor be metabolically active?

Osteoblastoma is a metabolically active benign bone tumor on 18F-FDG PET imaging.

What cancers do not show up on a PET scan?

On the other hand, tumors with low glycolytic activity such as adenomas, bronchioloalveolar carcinomas, carcinoid tumors, low grade lymphomas and small sized tumors have revealed false negative findings on PET scan.

What does metabolically mean?

Metabolic: Relating to metabolism, the whole range of biochemical processes that occur within us (or any living organism). The term “metabolic” is often used to refer specifically to the breakdown of food and its transformation into energy.

What is diffuse bone marrow uptake?

Diffuse bone marrow FDG uptake that mimics these malignant conditions has been reported to be caused by bone marrow stimulation resulting from bone marrow stimulants such as granulocyte-macrophage stimulating factor, granulocyte colony-stimulating factor,5–8 and erythropoietin.

What causes increased uptake on bone scan?

Thus, increased radiotracer uptake occurs with multiple pathologic processes such as fractures, infection, malignant disease and less commonly encountered osseous diseases like Paget disease, fibrous dysplasia, osteoid osteoma, and complex regional pain syndrome.

Why would a doctor order a PET scan?

Your healthcare provider may order a PET scan to check for signs of: Cancer, including breast cancer, lung cancer and thyroid cancer. Coronary artery disease, heart attack or other heart problems. Brain disorders, such as brain tumors, epilepsy, dementia and Alzheimer’s disease.

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