What is atovaquone proguanil 250 mg used for?

Atovaquone and proguanil is a combination medicine used to treat or prevent malaria, a disease caused by parasites. These medicines work by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito.

What can you not take with Malarone?

Some products that may interact with this drug include: penicillamine, “blood thinners” (such as warfarin), metoclopramide. Other medications can affect the removal of atovaquone/proguanil from your body, which may affect how atovaquone/proguanil works.

What are the side effects of atovaquone proguanil?

Blistering, peeling, loosening of skin.
convulsions.
hives or welts.
increased sensitivity of skin to sunlight.
itching, redness or other discoloration of skin.
large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs.
loss of bladder control.

What kind of drug is proguanil?

Atovaquone/proguanil belongs to a class of drugs known as antimalarials. The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world.

Is atovaquone an antibiotic?

Atovaquone is an antibiotic. Sometimes it is prescribed to treat pneumocystis pneumonia (PCP, see fact sheet 515). It is also sometimes used to treat toxoplasmosis (see fact sheet 517). Atovaquone can be given to prevent PCP or toxoplasmosis.

Is atovaquone-proguanil harmful to humans?

Atovaquone-proguanil is well tolerated, and side effects are rare. The most common adverse reactions reported are stomach pain, nausea, vomiting, and headache.

Is atovaquone proguanil harmful to humans?

Is atovaquone proguanil an antibiotic?

Atovaquone/proguanil, sold under the brand name Malarone among others, is a fixed-dose combination medication used to treat and prevent malaria, including chloroquine-resistant malaria. It contains atovaquone and proguanil….Atovaquone/proguanil.

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How long can you take atovaquone?

Adults and children 13 years of age and older—750 milligrams (mg) or 5 milliliters (mL) two times a day with food for 21 days. Children younger than 13 years of age—Use and dose must be determined by your doctor.

Is atovaquone a controlled substance?

Atovaquone/proguanil 250 mg / 100 mg is not a controlled substance under the Controlled Substances Act (CSA).

How effective is atovaquone?

In controlled clinical trials with more than 600 participants, a fixed-dose combination of atovaquone and proguanil hydrochloride was 98% effective in prophylaxis of malaria caused by Plasmodium falciparum and had a safety profile similar to that of placebo.

What is atovaquone-proguanil?

Atovaquone-proguanil is a combination of two drugs, atovaquone and proguanil, in a single tablet. It is available in the United States by prescription only.

What kind of pill is atovaquone 250 mg?

Atovaquone/Proguanil Hydrochloride 250 mg/100 mg film-coated tablets are buff coloured, round, biconvex, film-coated tablets debossed with ‘A-P’ over ‘2’ on one side and ‘M’ on the other side. 4. Clinical particulars

What is the composition of proguanil hydrochloride?

Qualitative and quantitative composition Each Atovaquone/Proguanil Hydrochloride film-coated tablet contains 250 mg atovaquone and 100 mg proguanil hydrochloride. Excipient with known effect: Each film-coated tablet also contains 4.018 mg of lactose monohydrate.

How many atovaquone-proguanil tablets should I take?

on their weight: 5–8 kg children should take a 1/2 pediatric tablet daily, > 8–10 kg: 3/4 pediatric tablet daily > 10–20 kg: 1 pediatric tablet daily > 20–30 kg: 2 pediatric tablets daily > 30–40 kg: 3 pediatric tablets daily >40 kg: 1 adult tablet daily. Atovaquone-proguanil should be taken with food or a milky drink.

What is atovaquone-proguanil 250 mg used for?

Is atovaquone used for malaria?

What is atovaquone-proguanil? Atovaquone-proguanil can be prescribed for either prevention or treatment of malaria.

How long can I take atovaquone-proguanil?

For malaria prevention: Adults—250 milligrams (mg) of atovaquone and 100 mg proguanil (1 adult strength tablet) per day, starting 1 to 2 days before entering malarial area and continuing for 7 days following return.

Does atovaquone need to be refrigerated?

Store atovaquone at room temperature. Do not refrigerate. This medicine may affect the way other medicines work.

Does proguanil treat malaria?

About proguanil Proguanil tablets help to protect you from malaria when you travel to areas where this can be a problem. It is usually used in combination with another antimalarial medicine to increase its effectiveness. Malaria is a serious infection.

Is atovaquone an antiviral?

Overall, these data suggest that atovaquone is a promising SARS-CoV-2 antiviral agent, which is able to inhibit viral replication and virus-induced inflammation at nontoxic concentrations in VeroE6 hTMPRSS2 cells and lung epithelial Calu-3 cells.

How many atovaquone/proguanil hydrochloride tablets should I take for malaria?

One Atovaquone/Proguanil Hydrochloride film-coated tablet daily. Atovaquone/Proguanil Hydrochloride is not recommended for malaria prophylaxis in persons under 40 kg bodyweight. Other pharmaceutical strengths may be more appropriate for malaria prophylaxis in persons weighing under 40 kg.

How many milligrams of atovaquone are in a Malarone tablet?

MALARONE Tablets and MALARONE Pediatric Tablets are for oral administration. Each MALARONE Tablet contains 250 mg of atovaquone and 100 mg of proguanil hydrochloride and each MALARONE Pediatric Tablet contains 62.5 mg of atovaquone and 25 mg of proguanil hydrochloride.

What is atovaquone and proguanil used to treat?

What is atovaquone and proguanil? Atovaquone and proguanil is a combination medicine used to treat or prevent malaria, a disease caused by parasites. These medicines work by interfering with the growth of parasites in the red blood cells of the human body.