What is the best antidepressant for pain and anxiety?

The most efficacious antidepressants for the treatment of neuropathic pain appear to be the tertiary-amine TCAs (amitriptyline, doxepin, imipramine), venlafaxine, bupropion, and duloxetine. These appear to be closely followed in efficacy by the secondary-amine TCAs (desipramine, nortriptyline).

What is the best drug for severe anxiety?

SSRIs approved by the Food and Drug Administration (FDA) for the treatment of panic disorder include fluoxetine (Prozac), paroxetine (Paxil, Pexeva) and sertraline (Zoloft). Serotonin and norepinephrine reuptake inhibitors (SNRIs). These medications are another class of antidepressants.

Does Wellbutrin help pain?

The results of this open-label trial offer preliminary evidence that SR bupropion at a dosage of 150 to 300 mg/day may be clinically effective for the treatment of neuropathic pain. Among the patients treated in the trial, two thirds reported that their pain was improved or much improved with bupropion.

Is there a medication that treats both depression and pain?

Serotonin and norepinephrine reuptake inhibitors (SNRIs). Some SNRIs , such as venlafaxine (Effexor XR), duloxetine (Cymbalta, Drizalma Sprinkle), milnacipran (Savella) and desvenlafaxine (Pristiq), may help relieve chronic pain. People with chronic pain often develop depression along with their chronic pain.

What is the safest anxiety med?

As of this writing, some of the anxiety medications with the fewest reported side effects and least risk of side effects include:

Most Benzodiazepines (Xanax, Valium)
Bupropion (Wellbutrin)
Citalopram (Celexa – SSRI)
Paroxetine (Paxil – SSRI)

What is the difference between Cymbalta and Wellbutrin?

Wellbutrin (Bupropion) Improves mood and relieves certain types of pain. Cymbalta (duloxetine) is good for treating depression, anxiety, and some forms of chronic pain, but it is more likely than other antidepressants to cause problems if you drink alcohol or have high blood pressure. Improves mood.