What are some current treatment strategies for cervical cancer?
Common types of treatments for cervical cancer include:
- Surgery for Cervical Cancer.
- Radiation Therapy for Cervical Cancer.
- Chemotherapy for Cervical Cancer.
- Targeted Drug Therapy for Cervical Cancer.
- Immunotherapy for Cervical Cancer.
How does cisplatin work as radiosensitizer?
The fact that a terminal cisplatin lesion results in inhibition of DNA-PKcs catalyzed kinase and autophosphorylation activity59 60, indicates that both NHEJ and HR catalyzed repair of DNA DSBs containing cisplatin lesions would be inhibited and therefore contribute to the radiosensitization activity of cisplatin.
Can cervical cancer spread after treatment?
Cancer that comes back after treatment is called a recurrence. But some cancer survivors may develop a new, unrelated cancer later. This is called a second cancer. Unfortunately, being treated for cervical cancer doesn’t mean you can’t get another cancer.
What happens when cervical cancer spreads?
The most common symptom that happens when cancer spreads to the lymph nodes, is that they feel hard or swollen. Cervical cancer can spread to lymph nodes in the area between the hip bones (pelvis). Cancer cells can also stop lymph fluid from draining away. This might lead to swelling in your legs due to fluid build up.
What are the 3 types of radiation treatment?
Three common types of internal radiation therapy include:
- Brachytherapy involves radioactive material that is implanted in the body.
- Intraoperative radiation therapy (IORT) is used to treat an exposed tumor during cancer surgery.
- Stereotactic radiosurgery (SRS) is not actually surgery.
What is the first line of treatment for cervical cancer?
Palliative platinum-based chemotherapy (CT) is the standard first-line treatment for metastatic/recurrent cervical cancer.
Which drug is considered a radiosensitizer?
Hypoxic cell sensitizers are able to increase the radiosensitivity of tumor cells deficient of oxygen by inducing the formation and stabilization of DNA-toxic radicals, mimicking the effect of oxygen. These drugs include nitroimidazole, misonidazole, etanidazole, nimorazole, and efaproxaril.
How does a radiosensitizer work?
A radiosensitizer, or a radiosensitizing agent, is a drug that makes cancer cells more vulnerable to radiation therapy. Radiation therapy uses high-energy radiation to shrink tumors by disrupting the DNA of cancer cells, causing them to die.
What is the final stage of cervical cancer?
Stage 4 means the cancer has spread to the bladder or back passage (rectum) or further away. The main treatments are surgery, radiotherapy, chemotherapy or a combination of these treatments. Or you might have treatment to control symptoms.
Will hysterectomy cure cervical cancer?
Nearly half of cervical cancers are diagnosed at an early stage, meaning the tumors are small and have not spread beyond the cervix. Although there are other treatment options, radical hysterectomy is the most common treatment for early-stage disease, and cure rates for the disease are around 80%.
What is the last stage of cervical cancer?
What stage is advanced cervical cancer?
Locally advanced cervical cancer usually includes stages 2B, 3 and 4A. Advanced stage cervical cancer usually means stage 4B.