What are the 6 classes of antiretroviral drugs?
These drugs are distributed into six distinct classes based on their molecular mechanism and resistance profiles: (1) nucleoside-analog reverse transcriptase inhibitors (NNRTIs), (2) non–nucleoside reverse transcriptase inhibitors (NNRTIs), (3) integrase inhibitors, (4) protease inhibitors (PIs), (5) fusion inhibitors.
How many classes of antiretrovirals are there?
There are six main types (‘classes’) of antiretroviral drugs. Each class of drug attacks HIV in a different way. Generally, drugs from two (or sometimes three) classes are combined to ensure a powerful attack on HIV.
What are the types of antiretrovirals?
Types of antiretroviral drug
- abacavir (Ziagen)
- emtricitabine (Emtriva)
- lamivudine (Epivir)
- stavudine (Stavudine)
- tenofovir disoproxil fumarate (Viread)
- zidovudine (Retrovir)
How are antivirals classified?
Antiviral drugs can be classified according to their chemical nature (e.g., small-molecules, peptides, biologics) or mechanisms of drug actions against specific viral proteins (e.g., polymerase inhibitors, protease inhibitors, glycoprotein inhibitors).
What are the 3 active antiretrovirals comprised of?
Most HAART regimens include drugs from at least two of the three classes of antiretroviral therapy (nucleoside analog reverse transcriptase (RT) inhibitors, non-nucleoside analog RT inhibitors, and protease inhibitors).
Why is nevirapine not used in PEP?
Nevirapine should not be used for post-exposure prophylaxis for adults, adolescents and older children because of the risk of life-threatening serious adverse events associated with HIV- negative adults using this drug (55,56).
What are the three major categories of antiretroviral drugs?
Pharmacologic drug classes include: Nucleoside reverse transcriptase inhibitors (NRTIs) Non-nucleoside reverse transcriptase inhibitors (NNRTIs) Protease inhibitors (PIs)
What is Acriptega?
Acriptega Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
What is the therapeutic classification of drugs?
Anatomical Therapeutic Chemical Classification System. The Anatomical Therapeutic Chemical (ATC) Classification System is a drug classification system that classifies the active ingredients of drugs according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties.
What are the best medications for HIV?
Gilead’s Truvada is the top-selling HIV drug in the world. A new HIV drug could be on the way soon from Gilead. The biotech is scheduled to wrap up a late-stage study of bictegravir in combination with F/TAF (Descovey) this year.
What are anti – HIV drugs?
HAART — often referred to as the anti-HIV “cocktail” — is a combination of three or more drugs, such as protease inhibitors and other anti-retroviral medications. The treatment is highly effective in slowing the rate at which the HIV virus replicates itself, which may slow the spread of HIV in the body.