Why was phenylpropanolamine taken off the market?

Why was phenylpropanolamine taken off the market?

Phenylpropanolamine has been voluntarily removed from the market in the United States by its manufactures because of concerns raised about its ability to precipitate a stroke when used, or perhaps abused, as an appetite suppressant Kernan et al (2000).

What do I do if my prescription is recalled?

If a prescription medication that you have been taking is recalled, do not panic. Stop taking the medication immediately, and call your doctor or contact a pharmacist and ask for a recommended replacement. Read the available materials from the FDA or the manufacturer to understand the reason for the recall.

Is it safe to take phenylpropanolamine?

The Nonprescription Drugs Advisory Committee met on October 19 to discuss safety issues related to phenylpropanolamine use. The committee reviewed Yale’s Hemorrhagic Stroke Project results and concluded that phenylpropanolamine cannot be considered to be safe for continued use.

What are the contraindications of phenylpropanolamine?

The following conditions are contraindicated with this drug….Conditions:

• overactive thyroid gland.
• increased pressure in the eye.
• closed angle glaucoma.
• high blood pressure.
• stenosing peptic ulcer.
• blockage of the urinary bladder.
• enlarged prostate.
• an inability to completely empty the bladder.

Why was PPA banned?

In 2005, the FDA removed PPA from over-the-counter sale. Because of its potential use in amphetamine manufacture, it is controlled by the Combat Methamphetamine Epidemic Act of 2005. It is still available for veterinary use in dogs, however, as a treatment for urinary incontinence.

Can you still buy contact 400 capsules?

But the products are still on sale in Britain. “We sell products containing PPA in over 50 countries worldwide, and we are still talking to regulatory bodies in these countries,” says Alan Archer of SmithKline Beecham, which produces Contac 400.

Who is responsible for notifying patients about recalled medications?

The FDA
The FDA does alert the public about recalls along with evaluating the effectiveness of a recall by looking at a company’s efforts to properly notify customers and remove the defective product from the market but it’s up the specific pharmacy to inform patients about their recalled medication.

How do I know if my medication has been recalled?

The FDA, manufacturer or dispensing pharmacy may notify patients by telephone, mail, fax or email if a medication has been recalled. The manufacturer usually posts recall information on their website. The FDA may publicly announce a recall via news and other media.

Can you still buy phenylpropanolamine?

It is available in nonprescription products alone and in combination with other ingredients for weight loss. The Food and Drug Administration (FDA) has taken steps to remove phenylpropanolamine from all drug products and has issued a public health advisory concerning phenylpropanolamine hydrochloride.

What are the side effects of phenylpropanolamine?

COMMON side effects

• constipation.
• drowsiness.
• inducing of a relaxed easy state.
• excessive sweating.
• nausea.
• vomiting.
• stomach cramps.
• an increase in the thickness of lung secretions.

What class of drug is phenylpropanolamine?

Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant.

Is Nafarin a paracetamol?

Nafarin-A (Reformulated) combines the complementary actions and dosage of a nasal decongestant (phenylpropanolamine), an antihistamine (chlorphenamine) and an analgesic-antipyretic (paracetamol).