What is zona fasciculata?
The zona fasciculata (sometimes, fascicular or fasiculate zone) constitutes the middle and also the widest zone of the adrenal cortex, sitting directly beneath the zona glomerulosa. Constituent cells are organized into bundles or “fascicles”.
What happens in the zona glomerulosa?
The primary function of the zona glomerulosa is the synthesis of mineralocorticoid hormones, which play an important role in the maintenance of electrolyte and water balance in the body. Mineralocorticoids are steroid hormones, and so are synthesised from cholesterol.
What regulates the zona glomerulosa?
Aldosterone production in zona glomerulosa (ZG) cells of adrenal glands is regulated by various extracellular stimuli (K(+), ANG II, ACTH) that all converge on two major intracellular signaling pathways: an increase in cAMP production and calcium (Ca(2+)) mobilization.
What is the zona reticularis secretes?
The zona reticularis is the site of biosynthesis of androgen precursors such as dehydroepiandrosterone (DHEA) and androstenedione from cholesterol. These androgens are released into the bloodstream and transported to gonads where they are converted into testosterone or oestrogen.
What is adrenal medulla?
The adrenal medulla, the inner part of an adrenal gland, controls hormones that initiate the flight or fight response. The main hormones secreted by the adrenal medulla include epinephrine (adrenaline) and norepinephrine (noradrenaline), which have similar functions.
Why is it called zona glomerulosa?
In response to increased potassium levels, renin or decreased blood flow to the kidneys, cells of the zona glomerulosa produce and secrete the mineralocorticoid aldosterone into the blood as part of the renin–angiotensin system….
| Zona glomerulosa | |
|---|---|
| Layers of cortex. | |
| Details | |
| Identifiers | |
| Latin | Zona glomerulosa |
Is cortisol a drug?
Cortisol is a steroid hormone, in the glucocorticoid class of hormones. When used as a medication, it is known as hydrocortisone. It is produced in many animals, mainly by the zona fasciculata of the adrenal cortex in the adrenal gland. It is produced in other tissues in lower quantities.
What is the function of zona reticularis?
zona reticularis: The inner most layer of the adrenal cortex, responsible for producing androgens such as DHEA.
What hormone Does the zona reticularis produce?
androgens
Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone (DHEA) and androstenedione from cholesterol. DHEA is further converted to DHEA-sulfate via a sulfotransferase, SULT2A1.
How do you say zona reticularis?
zona reticularis Pronunciation. zona retic·u·laris.
What does zona fasciculata produce?
The zona fasciculata of the adrenocortex primary produces glucocorticoids (cortisol in humans and corticosterone in rodents). The secretion of cortisol is pulsatile, with a steady frequency of about one pulse per hour in adults.