What is treatment for peripheral precocious puberty?

What is treatment for peripheral precocious puberty?

Treating peripheral precocious puberty Treatment for peripheral precocious puberty depends on what’s causing excess estrogen or androgen production. Options include tumor removal, blocking the actions of estrogen or androgen on the body, or treatment of hypothyroidism with replacement thyroid hormone.

What is the drug of choice for precocious puberty in girls?

Long-acting gonadotrophin releasing hormone (GnRH) agonists are the current therapy of choice for central precocious puberty, having demonstrated effectiveness in halting the precocious development associated with this condition with minimal side effects.

What is peripheral precocious puberty?

Peripheral precocious puberty (PPP) is the result of the presence of precocious puberty due to the increase of sex steroids with no evidence of activation of the hypothalamic-pituitary-gonadal axis.

How do you treat McCune-Albright?

How is McCune-Albright syndrome treated?

1. Medicine to treat bone growth symptoms like bisphosphonates, which reduce the risk of bone fractures.
2. Medicine to treat early puberty like aromatase inhibitors.
3. Medicine to treat hyperthyroidism like antithyroids.

Is precocious puberty serious?

The pattern and timing of the steps in the process are otherwise normal. For the majority of children with this condition, there’s no underlying medical problem and no identifiable reason for the early puberty.

How is peripheral precocious puberty diagnosed?

X-rays of your child’s hand and wrist also are important for diagnosing precocious puberty. These X-rays can help the doctor determine your child’s bone age, which shows if the bones are growing too quickly.

What causes precocious puberty in McCune-Albright?

Girls with McCune-Albright syndrome may reach puberty early. These girls often have menstrual bleeding by age 2. This early onset of menstruation is believed to be caused by excess estrogen, a female sex hormone, produced by cysts that develop in one of the ovaries .

Why does McCune-Albright syndrome cause precocious puberty?

Precocious puberty in McCune-Albright syndrome is gonadotropin-independent. This means that it is not caused by early release of gonadotropins (luteinizing hormone and follicle-stimulating hormone), but, instead, the cause is the early secretion of high levels of sex hormones (male androgens and female estrogens).

What can trigger early puberty?

Factors that increase a child’s risk of precocious puberty include:

• Being a girl. Girls are much more likely to develop precocious puberty.
• Being African-American.
• Being obese.
• Being exposed to sex hormones.
• Having other medical conditions.
• Having received radiation therapy of the central nervous system.