What is Tetrahydrocarbazole?
1,2,3,4-Tetrahydrocarbazole can be used as a starting material to prepare: Spiro[cyclopentane-1,2′-indolin-3′-one] by photooxygenation. 9-Acyl-1,2,3,4-tetrahydrocarbazoles by N-acylation reactions. Carbazole via palladium-catalyzed asymmetric hydrogenation reaction.
What are Carbazoles used for?
Carbazole usually applied as π-conjugated bridge to construct electron donor–π–electron acceptor (D–π–A) organic dyes. Organic dyes based on carbazole have shown important properties in dye-sensitized solar cells (Wang et al., 2008; Tang et al., 2010; Teng et al., 2009) [1–3].
When was the carbazole first discovered?
The European dye stuff industry originally provided the main stimulus for development of the chemistry of carbazoles since the discovery of the first member of the group, carbazole (1) from coal tar in 1872 by Graebe and Glazer (35).
What is the structure of carbazole?
Carbazole is an aromatic heterocyclic organic compound. It has a tricyclic structure, consisting of two six-membered benzene rings fused on either side of a five-membered nitrogen-containing ring.
What is indole group?
Indole is an aromatic heterocyclic organic compound with formula C8H7N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring. Indole is widely distributed in the natural environment and can be produced by a variety of bacteria.
Why is carbazole aromatic?
Carbazole is a tricyclic aromatic heterocyclic compound consisting of two benzene rings fused on either side of a five-membered nitrogen ring. Its intriguing structure exhibits high triplet energy. The aromaticity of a given compound is quantified using isosurface mapping of the magnetic shielding tensor.
Is carbazole an acid or base?
The N-atom of carbazole is weakly basic as imino hydrogen and is easily replaceable by alkali metals. In electrophilic substitution reactions, the C3-position is mainly affected and thereafter the C6-position. Since carbazole is less basic than indole and pyrrole, it is protonated in strong acid at nitrogen.
Which drugs indole alkaloids?
Important indole alkaloids which have been isolated from plants include the antihypertensive drug, reserpine from Rauvolfia serpentina (Sagi et al., 2016) and the powerful antitumor drugs, vinblastine and vincristine from Catharanthus roseus (El-Sayed and Verpoorte, 2007).
Where is indole found?
indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter.
Is pyrazine a Diazine?
Pyrazine is a diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms. It has a role as a Daphnia magna metabolite. It is a member of pyrazines and a diazine. A heterocyclic aromatic organic compound with the chemical formula C4H4N2.
Is carbazole a heterocyclic compound?
?) Carbazole is an aromatic heterocyclic organic compound. It has a tricyclic structure, consisting of two six-membered benzene rings fused on either side of a five-membered nitrogen -containing ring.
What is tetrahydrocannabinol?
Tetrahydrocannabinol. Like most pharmacologically-active secondary metabolites of plants, THC is a lipid found in cannabis, assumed to be involved in the plant’s self-defense, putatively against insect predation, ultraviolet light, and environmental stress. THC, along with its double bond isomers and their stereoisomers,…
How is carbazole synthesized in the laboratory?
A classic laboratory organic synthesis for carbazole is the Borsche–Drechsel cyclization. In the first step, phenylhydrazine is condensed with cyclohexanone to the corresponding imine.
What are the uses of carbazole in organic chemistry?
The triazole is unstable and at elevated temperatures, nitrogen is released and the carbazole is formed. Aminoethylcarbazole is used in the production of pigment violet 23 . Rimcazole is also made from carbazole proper. Carprofen is another use.