What does end-organ perfusion mean?

What does end-organ perfusion mean?

INTRODUCTION. Cardiogenic shock is a clinical condition of inadequate tissue (end-organ) perfusion due to the inability of the heart to pump an adequate amount of blood.

What is considered an end-organ?

end organ. noun. Medical Definition of end organ (Entry 2 of 2) : a structure forming the peripheral terminus of a path of nerve conduction and consisting of an effector or a receptor with its associated nerve terminations.

What are signs of poor end-organ perfusion?

Signs of end-organ hypoperfusion Decreased capillary refill, purpura cyanosis, or mottling may be seen. Altered mental status, obtundation, restlessness. Oliguria or anuria due to hypoperfusion. Ileus or absent bowel sounds.

What is meant by end organ damage?

End organ damage is defined as presence of any one or more of the following features: hypercalcemia, renal failure, anemia, and lytic bone lesions (which can be diagnosed on bone radiographs). From: Handbook of Clinical Neurology, 2014.

What is end organ damage in diabetes?

Over time, the surge and crash of dissolved glucose and insulin that occurs in diabetes can end up causing irreparable damage to many body organs and systems. Doctors refer to this as “end-organ damage” because it can effect nearly every organ system in the body: Hypertension (High Blood Pressure) and Heart Disease.

What indicates adequate end-organ and tissue perfusion?

Popular biomarkers of tissue perfusion such as serum lactate and central venous oxygen saturation are indicators of global tissue perfusion. Monitoring of peripheral circulation especially in non-vital organs added new insights for monitoring of tissue perfusion.

What is end-organ diabetes?

Definition. Irreparable damage to multiple organs/systems which is the result of chronic complications of diabetes. The affected organs/systems include the cardiovascular system, kidneys, eyes, nervous system, joints and feet. [ from NCI]

What are target organs?

A target organ is an organ in the body that is most affected by a specific chemical, drug, bacteria, or other substance. Lungs, liver, kidney, heart, blood, or circulatory system, brain or central nervous system, and skin (yes, the skin is considered an organ.)

What signs of end organ damage should the nurse expect to become evident when caring for a patient with sepsis?

What are the signs and symptoms of end-organ hypoperfusion in bacterial sepsis?

  • Warm, flushed skin may be present in the early phases of sepsis.
  • Altered mental status, obtundation, restlessness.
  • Oliguria or anuria due to hypoperfusion.
  • Ileus or absent bowel sounds.

What are the end organ damage caused by long standing hypertension?

The classic manifestations of hypertensive end organ damage include the following: vascular and hemorrhagic stroke, retinopathy, coronary heart disease/myocardial infarction and heart failure, proteinuria and renal failure and in the vasculature, atherosclerotic change including the development of stenoses and …

What causes organ damage in diabetes?

Diabetes affects your heart and your whole circulation. That includes small blood vessels in your kidneys, eyes, and nerves, and the big ones that feed your heart and brain and keep you alive. The damage starts with high blood sugar (glucose) and insulin levels.

What is organ perfusion?

Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue.

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