What are the side effects of rilpivirine?

What are the side effects of rilpivirine?

Common side effects of Edurant include:

• nausea,
• vomiting,
• stomach pain,
• diarrhea,
• fatigue,
• tiredness,
• headache,
• dizziness,

How do you take rilpivirine?

Take rilpivirine with a meal. (A protein drink alone does not replace a meal.) If you are taking any other medicines or supplements, including antacids, carefully follow instructions on how to take them with rilpivirine. Always take rilpivirine in combination with other HIV medicines.

What class of drug is rilpivirine?

Rilpivirine is in a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It works by decreasing the amount of HIV in the blood.

What is rilpivirine used for?

Rilpivirine is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body. Rilpivirine is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Rilpivirine is not a cure for HIV or AIDS.

What medications contain rilpivirine?

Rilpivirine

• Brand names: Edurant. Drug class(es): NNRTIs.
• Brand names: Cabenuva. Drug class(es): antiviral combinations.
• Brand names: Juluca. Drug class(es): antiviral combinations.
• Brand names: Odefsey. Drug class(es): antiviral combinations.
• Brand names: Complera. Drug class(es): antiviral combinations.

What are the contraindications of omeprazole?

Who should not take OMEPRAZOLE?

• diarrhea from an infection with Clostridium difficile bacteria.
• inadequate vitamin B12.
• low amount of magnesium in the blood.
• liver problems.
• a type of kidney inflammation called interstitial nephritis.
• subacute cutaneous lupus erythematosus.
• systemic lupus erythematosus, an autoimmune disease.

Is rilpivirine generic?

No. There is currently no therapeutically equivalent version of Edurant available in the United States. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Edurant.

What are the major side effects of omeprazole?

Side Effects

• Back, leg, or stomach pain.
• bleeding or crusting sores on the lips.
• blisters.
• bloody or cloudy urine.
• continuing ulcers or sores in the mouth.
• difficult, burning, or painful urination.
• frequent urge to urinate.
• general feeling of discomfort or illness.

Is omeprazole and esomeprazole the same thing?

Omeprazole (Prilosec) and esomeprazole (Nexium) are similar drugs. However, there are minor differences in their chemical makeup. Prilosec contains two isomers of the drug omeprazole, while Nexium only contains one isomer.

What is tenofovir disoproxil fumarate?

EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE (em tri SIT uh bean; te NOE fo veer) is 2 antiretroviral medicines in 1 tablet. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.

What drugs interfere with rilpivirine in Edurant?

Coadministration of EDURANT and drugs that inhibit CYP3A may result in increased plasma concentrations of rilpivirine. Coadministration of EDURANT with drugs that increase gastric pH may result in decreased plasma concentrations of rilpivirine and loss of virologic response and possible resistance to rilpivirine and to the class of NNRTIs.

What are the drug interactions between rilpivirine and medications?

DRUG INTERACTIONS [see Dosage and Administration (2), Contraindications (4) and Clinical Pharmacology (12.3).] Rilpivirine is primarily metabolized by cytochrome P450 (CYP)3A, and drugs that induce or inhibit CYP3A may thus affect the clearance of rilpivirine.

What are the potential adverse effects of CYP3A on rilpivirine?

Potential for significant decreases in rilpivirine plasma concentrations due to CYP3A enzyme induction, which may result in loss of virologic response. Potential for significant decreases in rilpivirine plasma concentrations due to gastric pH increase, which may result in loss of virologic response.

Is Rilpivirine a diarylpyrimidine NNRTI?

Like etravirine, rilpivirine is a diarylpyrimidine NNRTI; structural flexibility of these drugs allows for binding to the allosteric NNRTI binding pocket in a variety of conformations.