What are the contraindications of ceftriaxone?

What are the contraindications of ceftriaxone?

Who should not take CEFTRIAXONE?

  • diarrhea from an infection with Clostridium difficile bacteria.
  • a type of blood disorder where the red blood cells burst called hemolytic anemia.
  • liver problems.
  • disease of the gallbladder.
  • severe renal impairment.
  • yellowing of the skin in a newborn child.

What is the best treatment for Neisseria meningitidis?

Treatment following diagnosis Currently, a third-generation cephalosporin (ceftriaxone or cefotaxime) is the drug of choice for the treatment of meningococcal meningitis and septicemia. Penicillin G, ampicillin, chloramphenicol, fluoroquinolone, and aztreonam are alternatives therapies (IDSA guidelines).

What is the drug of choice for bacterial meningitis?

Since then, penicillin has remained the drug of choice for the treatment of meningococcal meningitis.

Why is ceftriaxone given for meningitis?

Ceftriaxone reaches a high bactericidal titer in the cerebrospinal fluid and persists at the site of infection longer than any other beta-lactam antibiotic.

Why is vancomycin given for meningitis?

Treatment of meningitis with vancomycin has been effective in clinical situations that precluded the use of the commonly administered agents, i.e., in infections due to resistant strains or to unusual organisms, in patients allergic to penicillin, and in patients for whom therapy with a first-choice antibiotic has …

What should you assess before administering ceftriaxone?

Examination and Evaluation

  1. Watch for seizures; notify physician immediately if patient develops or increases seizure activity.
  2. Monitor signs of pseudomembranous colitis, including diarrhea, abdominal pain, fever, pus or mucus in stools, and other severe or prolonged GI problems (nausea, vomiting, heartburn).

Is the recommended antibiotic for prophylaxis in Neisseria meningitidis?

Antibiotic chemoprophylaxis with rifampin, ciprofloxacin, or ceftriaxone is required for household and other close contacts. Although the majority of cases of meningococcal disease are sporadic, outbreaks can occur, and vaccination of the affected population often is necessary.

Why is ceftriaxone used for meningitis?

How is Neisseria gonorrhoeae diagnosed and treated?

Diagnosis and Treatment of Neisseria gonorrhoeae Infections. The most commonly infected joints include wrists, ankles, and the joints of the hands and feet. Urogenital N. gonorrhoeae infections can be diagnosed using culture or nonculture (e.g., the nucleic acid amplification test) techniques.

What happens if Neisseria gonorrhoeae is left untreated?

Diagnosis and Treatment of Neisseria gonorrhoeae Infections. If left untreated, N. gonorrhoeae infections can disseminate to other areas of the body, which commonly causes synovium and skin infections. Disseminated gonococcal infection presents as a few skin lesions that are limited to the extremities.

What is the drug of choice for gonorrhea?

Pharmacologic Treatment Regimens. Because of resistance with oral cephalosporins, only 1 regimen, dual treatment with ceftriaxone and azithromycin, is recommended for treatment of gonorrhea in the United States.

What is the most common site of Neisseria gonorrhoeae infection?

The most common site of Neisseria gonorrhoeae infection is the urogenital tract. Men with this infection may experience dysuria with penile discharge, and women may have mild vaginal mucopurulent discharge, severe pelvic pain, or no symptoms. Other N. gonorrhoeae infections include anorectal, conjunctival, pharyngeal, and ovarian/uterine.

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