How does diabetes cause dilated cardiomyopathy?

How does diabetes cause dilated cardiomyopathy?

Etiologically, four main causes are responsible for the development of heart failure in diabetic cardiomyopathy: microangiopathy and related endothelial dysfunction, autonomic neuropathy, metabolic alterations that include abnormal glucose use and increased fatty acid oxidation, generation and accumulation of free …

What is the most common cause of dilated cardiomyopathy?

The most common causes of dilated cardiomyopathy are: Heart disease caused by a narrowing or blockage in the coronary arteries. Poorly controlled high blood pressure.

How long can you live with dilated cardiomyopathy?

Clinically, DCM is characterized by a progressive course of ventricular dilatation and systolic dysfunction. The life expectancy is limited and varies according to the underlying etiology with a median survival time of about 5 years after diagnosis.

How does diabetes affect cardiomyopathy?

Type 1 and type 2 diabetic patients are at increased risk of cardiomyopathy and heart failure is a major cause of death for these patients. Cardiomyopathy in diabetes is associated with a cluster of features including decreased diastolic compliance, interstitial fibrosis and myocyte hypertrophy.

What are the 3 main causes of dilated cardiomyopathy?


  • Diabetes.
  • Obesity.
  • Heart rhythm problems (arrhythmias)
  • High blood pressure (hypertension)
  • Complications of late-stage pregnancy.
  • Excessive iron in your heart and other organs (hemochromatosis)
  • Certain infections.

Can you live 20 years with dilated cardiomyopathy?

In general, about half of all people diagnosed with congestive heart failure will survive five years. About 30% will survive for 10 years. In patients who receive a heart transplant, about 21% of patients are alive 20 years later.

How is diabetes cardiomyopathy diagnosed?

Echocardiography. Nowadays, this non-invasive approach is the gold standard diagnostic tool to identify structural cardiac disorders. It provides a reliable identification of the structural abnormalities seen in early stages of DCM, such as impaired diastolic filling and left ventricle hypertrophy.

Does diabetic cardiomyopathy exist?

Diabetic cardiomyopathy is defined by the existence of abnormal myocardial structure and performance in the absence of other cardiac risk factors, such as coronary artery disease, hypertension, and significant valvular disease, in individuals with diabetes mellitus.

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